Genentech

2024 Summer Intern - BioAnalytical Sciences


Pay$22.00 - $55.00 / hour
LocationSouth San Francisco/California
Employment typeFull-Time

This job is now closed

  • Job Description

      Req#: 202311-124611

      2024 Summer Intern - BioAnalytical Sciences


      Summer internship opportunities for students with demonstrated enthusiasm and curiosity in developing medicines in the biotech industry in the BioAnalytical Sciences (BAS) department at Genentech located on-site in South San Francisco.

      The BioAnalytical Sciences Department, within Development Sciences, uses world-class science to help bring life-changing medicines to patients. We foster an innovative and collaborative environment that values and recognizes a diversity of contributions. You will gain hands-on lab experience, develop professional skills, and have the opportunity to network and learn from professionals in the industry. BAS has several groups working on preclinical and clinical programs developing bioanalytical assays with a variety of cutting edge technologies including:

      • Ligand-binding Assays: Have you ever wondered how medicines are measured in patient blood or other biological samples collected during a clinical trial? Bioanalytical assays specifically measure the protein drug molecule out of the thousands of different molecules present in blood. You may test a range of antibodies to design and develop Enzyme-Linked ImmunoSorbent Assay (ELISA) or other types of immunoassays and help understand pharmacokinetics (PK), biomarkers, or immunogenicity of a drug being tested in an animal or a clinical study.

      • Liquid Chromatography-Mass Spectrometry (LC-MS): Are you interested in detecting drug molecules in biological samples and also characterizing protein structures and sequence? You may design immunoaffinity LC-MS assays based on molecular separations, enzymatic digestions and peptide analysis to help understand PK, biomarkers, metabolism or proteomics for a drug being tested in an animal or a clinical study. Mass spectrometry experience is desired for some advanced projects.

      • Cell Biology: Do you want to see how the cells in the body react to drugs or act on the drugs? You may investigate these biological questions using cell-based assays such as cellular internalization and processing, high content imaging, neutralizing antibody (NAb) assay or antibody effector function assays. Your work will consist in the development of cell-based assays and will utilize cell culture and flow cytometry. Confocal imaging expertise is desired for some advanced projects.

      • Predictive Sciences: Are you interested in using big data and modeling to understand how drugs act within the body? The predictive sciences group employs forward and reverse translation research to develop in silico and in vitro models to accurately predict the clinical immunogenicity and PK of new drugs. You may use and develop skills such as Immunology, Molecular Biology, cell culture, flow cytometry, confocal microscopy, and scripting (R and/or Python).

      • Customized Assay Reagents: Most assays used in nonclinical and clinical studies need custom reagents like antibodies with different types of molecular tags added to provide the best assay results. Are you interested in designing tags for proteins and antibodies to give them new molecular handles or fluorescent tags? You may work in developing and/or characterizing critical reagents used in clinical assays. This will require skills in protein conjugation, protein characterization, chromatography, light scattering, or binding kinetics (Biacore).

      • BioAnalytical Operations: Do you want to learn how to operationalize science through the transfer of our assays to Contract Research Organizations (CROs), manage these resources to support sample analysis for nonclinical and clinical studies and oversee our study data deliverables? You may provide oversight of our partner labs to enable timely sample analysis or operationalize study sample analysis plans and facilitate quality data delivery with global study teams. This work requires effective communication skills and will provide an opportunity to learn various information systems enabling efficient oversight of key deliverables and timelines.


      Key Responsibilities

      You will lead a project over the course of ~12 weeks under the mentorship of an intern manager. For laboratory based positions, you will execute experiments and document your scientific work. You will also attend group meetings and department seminars. Internships will be on-site and most involve laboratory work. It is expected that the interns will showcase their work at the end of the internship to both the department and at a wider Genentech campus event.

      Program Highlights

      • Intensive 12-weeks full time (40 hours per week) paid internship.

      • Program start dates are in May/June (Summer)

      • A stipend, based on location, will be provided to help alleviate costs associated with the internship.

      • Ownership of challenging and impactful business-critical projects.

      • Work with some of the most talented people in the biotechnology industry.

      Who You Are

      • Required education: Currently enrolled in an undergraduate or graduate program OR are within 2 years of graduation from your last degree.

      • Required majors: Biology, Chemistry, Biochemistry, Immunology, Pharmaceutical Sciences, or other related field at an accredited university or college;

      • Able to work on-site for the duration of the internship.

      • Candidates will embrace Roche’s core values of integrity, courage, and passion.

      Relocation benefits are not available for this job posting.

      The expected salary range for this position based on the primary location for this position in California is $22.00 - $55.00 per hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

      #GNE-R&D-Interns-2024

      Genentech is an equal opportunity employer, and we embrace the increasingly diverse world around us. Genentech prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin or ancestry, age, disability, marital status and veteran status.

  • About the company

      Genentech, Inc., is an American biotechnology corporation which became a subsidiary of Roche in 2009.

Notice

Talentify is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or protected veteran status.

Talentify provides reasonable accommodations to qualified applicants with disabilities, including disabled veterans. Request assistance at accessibility@talentify.io or 407-000-0000.

Federal law requires every new hire to complete Form I-9 and present proof of identity and U.S. work eligibility.

An Automated Employment Decision Tool (AEDT) will score your job-related skills and responses. Bias-audit & data-use details: www.talentify.io/bias-audit-report. NYC applicants may request an alternative process or accommodation at aedt@talentify.io or 407-000-0000.