• Job Description

  Req#: R0104113

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  Job Description

  TITLE: ASSOCIATE DIRECTOR, COMPUTATIONAL CHEMISTRY

  OBJECTIVES/PURPOSE :

  • As the ASSOCIATE DIRECTOR, COMPUTATIONAL CHEMISTRY, you will work as part of a multi-disciplinary team of Medicinal Chemists, Computational Chemists, Structural biologists, Pharmacologists and Biologists to provide Computational expertise to advance drug discovery projects.
  • You will contribute to drug discovery efforts across various modalities including small molecules, bifunctional degraders, peptides, RNA/oligonucleotides, and biologics.
  • You will implement and execute innovative computational methodologies and tools such as AI approaches to support drug discovery efforts.

  ACCOUNTABILITIES:

  • Responsible for visibility and representation of Computational Chemistry Accomplishments to Takeda executive team.
  • Demonstrate expert understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment.
  • Identify, develop, validate, and implement innovative computational approaches that improve research productivity and success.
  • Provide important technical knowledge and input to project teams to drive decision making in drug discovery projects.
  • Manage and mentor a Strong team of Computational Chemists to high productivity levels

  DIMENSIONS AND ASPECTS:

  • Strong expertise in a variety of computational tools and methodologies including Docking, Virtual screening, Molecular dynamics, Free energy perturbation, Homology modeling, Quantum mechanics, Pharmacophore elucidation, Data mining, Cheminformatics, Clustering, Similarity & Diversity analysis.
  • 10+ years of strong Industry experience contributing as Computational Chemist on Pharma projects.
  • Strong Impact on progressing Discovery Projects from Hits to Clinical Leads
  • Strong knowledge & experience in using a variety of tools for Hit ID
  • Provide project teams with computational strategies to inform, influence, and prioritize compound designs for potency/selectivity and improve ADME/Tox endpoints.
  • Contribute to the design, development and deployment of AI platforms to impact drug discovery.
  • Identify and implement novel computational chemistry algorithms, technologies, and workflows.
  • Strong Proficiency with state of the art Computational chemistry software.
  • Proficiency in scientific scripting and programming languages

  EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

  • PhD degree in a scientific discipline with 7+ years experience , or MS with 13+ years experience, or BS with 15+ years experience
  • 5 years of Industry experience required
  • 5 years of managerial experience required

  Base Salary Range: $143,500 to $205,000. Employees may also be eligible for Short Term and Long-Term Incentive benefits. Employees are eligible to participate in Medical, Dental, Vision, Life Insurance, 401(k), Charitable Contribution Match, Holidays, Personal Days & Vacation, Tuition Reimbursement Program and Paid Volunteer Time Off.

  The final salary offered for this position may take into account a number of factors including, but not limited to, location, skills, education, and experience.

  Takeda Compensation and Benefits Summary

  We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

  For Location:

  San Diego, CA

  U.S. Base Salary Range:

  $149,100.00 - $234,300.00

  The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained , certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

  U.S. based employee s may be eligible for s hort - t erm and/ or l ong- t erm incentive s . U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

  EEO Statement

  Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

  Locations

  San Diego, CA

  Worker Type

  Employee

  Worker Sub-Type

  Regular

  Time Type

  Full time

• About the company

  Hope and empathy. These two words are not often associated with pharmaceutical companies. But here at Takeda, our people are motivated to serve patients with integrity, respect, and empathy. Driven by our mission, we seek to bring hope of better health and a brighter future to those we impact. To do this, we focus on our chosen core therapeutic areas: Oncology Gastroenterology Neuroscience Develop life-saving vaccines No matter the region, business unit, function, or team, everyone at Takeda matters. Every one of our employees is a vital contributor to our bold, inspiring mission.

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