Agenus

Associate Scientist, Immune Cell-based Assays


PayCompetitive
LocationCambridge/England
Employment typeFull-Time

This job is now closed

  • Job Description

      Req#: 1105

      The role:

      We have an exciting opportunity for an Associate Scientist with a background in Cellular Immunology to join the Assay Development team at our R&D facility in Cambridge, UK. In this role you will work as part of a multi-disciplinary team supporting the delivery of our in-house immuno-oncology therapeutic antibody programs. The position is predominantly laboratory based and you will contribute to projects from an early target evaluation stage through to post-candidate nomination to IND and beyond.

      In the role you will:

      • Design and carry out 2D and 3D cell-based assays to profile the activity of our drug candidates using human cancer cell lines, blood-derived immune cells as well as patient tumor samples.
      • Develop, evaluate and implement experimental read-outs to maximise data generation and novel technologies and methods for process improvement.
      • Work closely in a matrix team to interpret complex data and select the best antibody candidates to take forward.
      • Give regular presentations locally as well as company-wide.
      • Contribute to routine laboratory tasks including reagent/consumables ordering and maintaining a clean laboratory environment.
      • Conduct accurate data analysis and documentation to ensure traceability, including writing SOPs, risk assessments, reports, ELN entries, and other necessary records.
      • Adhere to corporate standards regarding code of conduct and safety, aligning with Agenus' policies and procedures.
      • Expertise of working with human primary immune cells
      • Proven track record of running multicolor flow cytometry assays
      • Prior experience with 3D-cell culture systems (e.g. spheroids, organoids or tissue fragments) and/or immunohistochemistry/imaging would be an advantage
      • Strong written and verbal communication skills
      • Ability to work effectively both independently and as part of a multidisciplinary team

      Qualifications: About you

      • Ph.D. in relevant scientific discipline with academic or ideally industry related experience; Master’s degree or native equivalent with directly related experience; or Bachelor’s degree or native equivalent in scientific discipline related experience.
      • An Immunology background is highly desirable.
      • Excellent communication skills and the ability to work both independently and collaboratively within a team
      • Demonstrated strong aptitude for working in a process-driven manner, with a motivation to achieve success through efficient processes.

      #LI-JW1 #LI-Onsite

  • About the company

      Our mission is to the power of the immune system to bring affordable, curative therapies to cancer patients

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