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The Position

We’re advancing science to ensure everyone has access to the healthcare
they need.

The “Data and Analytics - Computational Science” section of Roche Informatics is looking for a computational biologist/bioinformatics scientist with strong prior experience in single-cell and genetics/genomics analysis to work with the Department of Regenerative Medicine (Immunology) in Genentech Research and Early Development (gRED). The focus of this position is support for the development of therapies aimed at treating inflammation-associated cellular damage and age-related diseases.

The Opportunity

• Analysis of public and internal single-cell RNA and ATAC-seq data to support specific therapeutic hypotheses

• Support for gene and cell therapy projects in regenerative medicine, with a focus on transcription factor over-expression and regulatory element design

• Research into the role of senescent cell populations in disease

• The development of NMF-related tools (topic analysis) for understanding gene expression and regulatory changes between diseased and healthy cells

• Evaluating mechanisms of epithelial repair in IBD/Ulcerative Colitis, COPD, and AMD

Who you are

• PhD in computational biology, bioinformatics, or related field, or MSc with 3-5 years of experience.

• Proficiency in R and Python and demonstrable experience in single-cell and genomic analyses

• History of scientific publications

• Previous experience with biology-focused computational analyses

• Clear communication skills and a desire to work in a team environment

• Machine learning experience is a plus

Relocation benefits are not available for this posting.

Who we are

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.

Roche Pharma Canada has its office in Mississauga, Ontario and employs over 850 employees. The Mississauga facility is bright, vibrant, fosters collaboration and teamwork, and is reflective of Roche's truly innovative culture.

As of January 4, 2022, Roche requires all new employees who work in Canada to be fully vaccinated against COVID-19 on the date they take office. This requirement is a condition of employment at Roche that applies regardless of whether the position is on a Roche campus or remotely. If you have a valid reason for not being fully immunized, which is limited to certain specific medical reasons or other valid reasons protected by applicable human rights laws, you may request an exemption and / or adaptation measures regarding this vaccination requirement.