• Job Description

  Req#: C9271-25-0336?language=en&page=71&sort=publicationDateDesc

  Job summary

  We are seeking an experienced genetic technologist who can demonstrate skilled use of genomic techniques to join the North Thames Rare Disease Laboratory Hub at Great Ormond Street Hospital.

  Depending on current skills and experience, you will be assigned to one of our process based teams who carry out both rare disease and cancer sample processing and testing: NGS/NIPD; Molecular targeted; Robotic; Cytogenetic; Preparation; WGS. Rotation between teams may be arranged.

  You will contribute to the smooth running of the North Thames Rare Disease Laboratory and must be able to demonstrate a high level of skill in molecular and/or cytogenetic techniques; hands on experience in an accredited diagnostic setting will be an advantage.

  The genetics laboratory provides an in-house diagnostic service for cancer, molecular genetic and cytogenetic testing in accordance with the NHS England Genomic Test Directory. Cytogenetic testing is provided for both prenatal and postnatal samples using SNP microarray, karyotyping, FISH, qPCR, QFPCR and MLPA. Molecular testing includes next generation sequencing and targeted tests. We are also engaged in the development and ramping up of the NHSE Genomic Medicine Service Whole Genome Sequencing programme for our North Thames patients.

  Main duties of the job

  • To follow established procedures and assist in the maintenance, preparation and review of operating policies
  • Comply with health and safety policies
  • Assist in quality assurance procedures
  • Registration of samples received into the laboratory
  • Sample processing including extraction, quantitation, storage and dispatch of DNA
  • Assume responsibility for a technique/area as directed by a Senior Technologist or the Lead Technologist (e.g. CF NewBorn Screening, Sample Reception). This may involve management of a small group of staff; to include the responsibility for appraisals, acting as an appointment panel member; ensuring that appropriate training is delivered; reviewing work performance and progress; work allocation and checking
  • Analysis of data and preparation for authorisation by scientific staff.
  • Computerised data entry of patient sample and result details

  About us

  GOSH is committed to recruiting the best person for the job, based solely on their ability and individual merit as measured against the criteria for the role; through a process that is fair, open, consistent and free from bias and discrimination.

  We are committed to being a diverse and inclusive employer and foster a culture where all staff are valued, respected and acknowledged. All applicants will receive consideration for employment without regard to race, colour, national origin, religion, sexual orientation, gender, gender identity, age, disability status or length of time spent unemployed.

  We particularly welcome applications from BAME communities, people with disabilities and/or long-term health conditions and LGBT+ community members.

  We have policies and procedures in place to ensure that all applicants and employees are treated fairly and consistently. We are proud to be accredited as a Disability Confident Employer, a member of Business Disability Forum and a Stonewall Diversity Champion.

  We have active and Executive supported BAME, LGBT+ and Allies, Disability and Long-Term Health Conditions and Women's staff networks. Staff networks are employee-led groups formed around interests, issues and a common bond or background. Staff network members create a positive and inclusive work environment at Great Ormond Street Hospital by actively contributing to the Trust's mission, values and efforts specific to inclusion. All of our staff networks are open to any employee.

  Details

  Date posted

  14 May 2025

  Pay scheme

  Agenda for change

  Band

  Band 5

  Salary

  £35,964 to £43,780 a year per annum inclusive

  Contract

  Permanent

  Working pattern

  Full-time

  Reference number

  271-GEN-7074941

  Job locations

  Great Ormond Street Hospital for Children NHS Foundation Trust

  Great Ormond Street Hospital

  London

  WC1N 3JH

  
  

  Job description

  Job responsibilities

  The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below.

  Job description

  Job responsibilities

  The full job description provides an overview of the key tasks and responsibilities of the role, and the person specification outlines the qualifications, skills, experience and knowledge required. For both documents please view the attachment/s below.

  Person Specification

  GOSH Culture and Values

  Essential

  • Our Always values

  Academic/Professional qualification/Training

  Essential

  • HNC/HND or Diploma in science (or equivalent)

  Desirable

  • Biological Science / Genetics Degree

  Knowledge & Experience

  Essential

  • Genetics Laboratory experience
  • Able to work under supervision
  • Basic knowledge regarding biochemical, cytogenetic and molecular genetic technology

  Desirable

  • Experience of supervision / training

  Skills/Abilities

  Essential

  • Evidence of molecular genetic / cytogenetic techniques in a diagnostic setting including: DNA extraction, PCR, MLPA, Sanger Sequencing, NGS, automated sample handling systems, ABI genetic analysers, G Banded karyotyping, microarray
  • Careful, meticulous and able to follow instructions
  • Computer literate
  • Able to communicate effectively both verbally, by email and by appropriate documentation
  • Willing to adapt to changes in methodology
  • Experience with laboratory information management systems

  Person Specification

  GOSH Culture and Values

  Essential

  • Our Always values

  Academic/Professional qualification/Training

  Essential

  • HNC/HND or Diploma in science (or equivalent)

  Desirable

  • Biological Science / Genetics Degree

  Knowledge & Experience

  Essential

  • Genetics Laboratory experience
  • Able to work under supervision
  • Basic knowledge regarding biochemical, cytogenetic and molecular genetic technology

  Desirable

  • Experience of supervision / training

  Skills/Abilities

  Essential

  • Evidence of molecular genetic / cytogenetic techniques in a diagnostic setting including: DNA extraction, PCR, MLPA, Sanger Sequencing, NGS, automated sample handling systems, ABI genetic analysers, G Banded karyotyping, microarray
  • Careful, meticulous and able to follow instructions
  • Computer literate
  • Able to communicate effectively both verbally, by email and by appropriate documentation
  • Willing to adapt to changes in methodology
  • Experience with laboratory information management systems

  Disclosure and Barring Service Check

  This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

  Certificate of Sponsorship

  Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

  From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

  Additional information

  Disclosure and Barring Service Check

  This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.

  Certificate of Sponsorship

  Applications from job seekers who require current Skilled worker sponsorship to work in the UK are welcome and will be considered alongside all other applications. For further information visit the UK Visas and Immigration website (Opens in a new tab).

  From 6 April 2017, skilled worker applicants, applying for entry clearance into the UK, have had to present a criminal record certificate from each country they have resided continuously or cumulatively for 12 months or more in the past 10 years. Adult dependants (over 18 years old) are also subject to this requirement. Guidance can be found here Criminal records checks for overseas applicants (Opens in a new tab).

  Employer details

  Employer name

  Great Ormond Street Hospital for Children NHS Foundation Trust

  Address

  Great Ormond Street Hospital for Children NHS Foundation Trust

  Great Ormond Street Hospital

  London

  WC1N 3JH

  
  

  Employer's website

  https://www.gosh.nhs.uk/ (Opens in a new tab)

  Employer details

  Employer name

  Great Ormond Street Hospital for Children NHS Foundation Trust

  Address

  Great Ormond Street Hospital for Children NHS Foundation Trust

  Great Ormond Street Hospital

  London

  WC1N 3JH

  
  

  Employer's website

  https://www.gosh.nhs.uk/ (Opens in a new tab)

• About the company

  National Health Service (NHS) is the umbrella term for the publicly-funded healthcare systems of the United Kingdom (UK). The founding principles were that services should be comprehensive, universal and free at the point of delivery—a health service based on clinical need, not ability to pay. Each service provides a comprehensive range of health services, free at the point of use for people ordinarily resident in the United Kingdom apart from dental treatment and optical care.

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