Unlock the future of drug development! Are you passionate about predicting chronic disease outcomes and making a meaningful impact? Ready to immerse yourself in the world of PK-PD modeling and collaborative innovation? Eager to contribute to cutting-edge research and shape the healthcare landscape?

Join us on this transformative journey—be our next Post-doc / PK-PD Scientist for Simulation Tool Project- Apply now!

The Position

This 3 years limited-term position is part of a larger project with the aim of developing a simulation tool to predict short- and long-term outcomes of chronic diseases, such as diabetes and obesity, and the impact of treatment on these outcomes, to inform drug development at different stages. The project involves three post-docs/scientists collaborating closely and with specialists from various areas, including data science, modelling, and medical sciences. External collaboration with organizations and universities is also possible.

In this position within the Pharmacometrics department at Novo Nordisk Data Science, you'll exclusively focus on the simulation tool project. You will have the opportunity to develop new PK-PD models based on clinical data and collaborate with two other post-docs/scientists within the project, who will deliver risk models and develop the overall simulation tool.

In addition you will:

• Develop and implement PK-PD models for relevant biomarkers based on clinical data
• Plan and execute the PK-PD modelling activities within the project
• Actively collaborate with project participants to execute the tasks within the project
• Write scientific publications to document the tool and your findings

With the collaboration with two other post-docs/scientists in the project, you'll contribute to risk models and the overall development of the simulation tool. Additionally, specialists with diverse backgrounds will be available for guidance. The role provides the opportunity to influence drug development across various stages within the organization.

This 3 years limited-term position is part of a larger project with the aim of developing a simulation tool to predict short- and long-term outcomes of chronic diseases, such as diabetes and obesity, and the impact of treatment on these outcomes, to inform drug development at different stages. The project includes three post-docs/scientists who are expected to collaborate closely together and with specialists from different areas, including, but not limited to, data science and modeling, and medical sciences. In addition, collaboration with external organizations and universities is also possible.

Physical Requirements

0-10% overnight travel required.

Qualifications

A master's degree in natural or computer sciences, engineering, mathematics, or statistics is required. Alternatively, a Ph.D. or equivalent degree with substantial experience in pharmacokinetics-pharmacodynamics (PK-PD) or equivalent research and/or development experience.

Relevant experience includes:

• Strong programming skills and experience writing advanced, well-performing and maintainable code in R, Python, Julia, C++ and/or C
• Experience in developing PK-PD models based on clinical data
• Background in mathematical modeling using differential equations
• Good written and oral communication skills
• Able to work in collaborative projects and sometimes under strict deadlines

Preferred experience includes:

• NONMEM/PsN/Pirana
• Classical statistical methods
• Completing or participating in scientific publications
• Detail oriented with strong documentation skills
• Developing interactive software or dashboards used by others, e.g. Shiny

Employment duration and location

This is a limited term position for 3 years starting from 1 January 2024 or as soon as possible thereafter. The candidate will be based in Soeborg, Denmark. Remote working can be discussed for the proper candidate.

About the Department

In the Development area of Novo Nordisk, we are responsible for managing clinical product development worldwide from early development phases to product launch and beyond. We provide medical and scientific documentation for clinical submissions and authorities while ensuring that the process lives up to global standards, regulations and business ethics.

The Pharmacometrics department is part of Novo Nordisk Data Science. Pharmacometrics (PMX) supports the entire Novo Nordisk development portfolio with model-based analyses and clinical trial simulations from planning and execution of first in human trials to registration. We are a team of dedicated modelling scientists with an important role in the development of new drugs at Novo Nordisk as responsible for designing, analysing, interpreting, communicating, and reporting pharmacometrics analysis at all stages of clinical drug development. We work in multidisciplinary teams with strong collaboration across all areas of the organization and engage in external collaborations to ensure access to cutting edge research and methods.

Working at Novo Nordisk

Novo Nordisk is its people. We know that life is anything but linear, and balancing what is important at different stages of our career is never easy. That’s why we make room for diverse life situations, always putting people first. We value our employees for the unique skills they bring to the table, and we work continuously to bring out the best in them. Working at Novo Nordisk is working toward something bigger than ourselves, and it’s a collective effort. Novo Nordisk relies on the joint potential and collaboration of its more than 55,000 employees. Together, we go further. Together, we’re life changing.

Contact

For further information, please contact Jonas Kildegaard, Director Pharmacometrics (+45 3079 7033)

Deadline

14 February 2024.

You do not need to attach a cover letter to your application, but please include a few sentences about why you are applying in your resume or CV. To ensure an efficient and fair recruitment process, please refrain from adding a photo in your CV.

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.