• Job Description

  Req#: 388249

  Post-Doc Research Associate

  Project: Engineered nanosystems for next generation vaccine adjuvants

  Temporary contract: 3 years

  This role will be located at GSK – Italy

  This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include …

  • Be part of cutting-edge science to advance GSK’s mission ‘to unite science, technology and talent to get ahead of disease together’.

  • Accelerate your post-doctoral research with GSK’s extensive R&D engine.

  • Bridge the gap from target identification to medicine/vaccine for patients in-need by leveraging GSK’s: Tools, Technologies, Libraries, Samples, People, Knowledge Base, & Training programs.

  Your Postdoctoral experience will be accompanied by tremendous support at GSK with the opportunity for daily collaborations with world-class scientists. GSK is committed to providing each postdoc with a mentor who will be focused on providing a comprehensive training program and are expected to nurture skills that will enable postdocs to become independent scientific investigators.

  Postdocs are actively encouraged to publish and present their research at internal and external meetings and participate in the GSK R&D postdoc community, which will include scientific and social programming.

  Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

  • Operating at pace and agile decision-making – using evidence and applying judgement to balance pace, rigor, and risk.

  • Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.

  • Continuously looking for opportunities to learn, build skills and share learning.

  • Sustaining energy and well-being.

  • Building strong relationships and collaboration, honest and open conversations.

  • Budgeting and cost-consciousness.

  Post-Doc Responsibilities:

  The goal of this Post-Doctoral role will be focused on the development of engineered nanosystems, specifically new vaccines adjuvants to targeted to a specific tissue or cell population, driving a next generation of delivery solutions for vaccines.

  Within Basic Pharmaceutical Science Drug Product Team in Research & Development, you will design, formulate, and characterize novel target moieties and delivery systems that will allow to:

  • Select the most promising chemical entities to enable targeted delivery and immunomodulation

  • Develop ways to incorporate them in complex nanoparticles

  • Understanding key attributes that relate to formulation performance via in vitro/in vivo studies

  In this context, you will have the possibility to play a key role in the development of a new generation of adjuvants, bringing your own ideas and expertise to develop engineered nanosystems for precise delivery. You are expected to participate in the conception, design, implementation, and interpretation of scientific and technical data, applying the knowledge and skills you have gained from your previous experiences. Furthermore, you will have the opportunity to be part of the Drug Product team, surrounded by a group of excellent scientists dedicated to meet the needs of the patients, and working to improve their quality of life.

  Basic Qualifications and any foundational experience required for this role are:

  • PhD in (Bio-)engineering, Chemistry, Biochemistry, Pharmaceutical Sciences or Life Sciences, with proven experience in conjugation chemistry and lipid nanoparticles formulation

  • Experience in analytical techniques used for nanoparticles characterization (e.g, size, polydispersity index, surface charge, stability and degradation),

  • Proficient written and verbal communication skills; ability to convey scientific messages across multidisciplinary functions.

  • Fluent in English

  • The ability to deal with complexity, strong problem-solving and self-directional abilities.

  • Ability to work in an international environment, with a strong team spirit.

  To be successful in the role, this person must have the ability to understand, interpret, and communicate complex scientific data; must be comfortable conversing with opinion leaders regarding technical information; possess a good balance of creative, analytical, and strong communication skills; ability to be productive and successful in an innovative environment and he/she must be a Team Player.

  Preferred Qualifications:

  • Knowledge of lipid-based nanosystems, and formulation via microfluidics

  • Experience in vaccines, adjuvants, or immunotherapy

  • Experience in design and implementation of in-vitro and/or in silico screening of chemical entities to define Structure-Activity Relationship and underlying biological mechanism of action

  • Experience on in vivo biodistribution studies

  Please use the cover letter to highlight how you fit the applicant profile and meet the skills and competencies for the role. Your cover letter along with your CV will be used to assess your application.

  Job posting end date: February 12th.

  Why Us?

  GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.

  Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

  If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

  GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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• About the company

  GlaxoSmithKline plc is a British multinational pharmaceutical company headquartered in Brentford, England.

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