Dalhousie University
Postdoctoral Fellow - Recombinant Spider Silk Protein Engineering For Biomedical Applications
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Job Description
- Req#: 18884
This is a postdoctoral fellowship in the Rainey laboratory at Dalhousie University (http://structbio.biochem.dal.ca/jrainey/ ), working in collaboration with Dr. John Frampton (http://www.framptonlab.com/ ) and funded by the Natural Sciences and Engineering Research Council of Canada (NSERC) in collaboration with 3DBioFibR Inc. (https://3dbiofibr.com/ ). The Rainey lab has developed a variety of recombinant spider silks and processed these into fibres by hand-drawing (e.g., Xu et al. (2017) Biomacromolecules 18: 3678) and wet-spinning (e.g., Xu et al. (2019) Small 15: 1805294; Simmons et al. (2019) ACS Biomater Sci Eng 5: 4985; Ghimire et al. (2024) Mater Today Bio 26: 101073; Sulekha et a. (2025) Adv Funct Mater 35: 2420254) or into films (e.g., Baker et al. (2022) Adv Funct Mater 32: 22051778). The present project will expand silk protein functionality by evaluating the potential to engineer silk proteins for desired materials properties and apply 3DBioFibR’s contact drawing technology (https://3dbiofibr.com/our-platform/ ) to produce silks with different materials formulations. We are well-equipped for recombinant protein production and purification and for biophysical and materials characterization (CD, FTIR and fluorescence spectroscopy instruments; light scattering instrument; optical microscopy; atomic force microscopy; tensile testing; and, a newly installed solution- and solid-state 600 MHz NMR spectrometer). Excellent Dalhousie-based protein biophysics (https://bit.ly/3AvBEpt ), electron microscopy, NMR spectroscopy, proteomics, and optical microscopy core facilities (https://medicine.dal.ca/research-dal-med/facilities.html ) are also routinely used by our lab.About the company
Dalhousie University is a public research university in Nova Scotia, Canada, with three campuses in Halifax, a fourth in Bible Hill, and medical teaching facilities in Saint John, New Brunswick.
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