GSK is currently looking for a Principal Scientist to join our team in Upper Providence, PA. This role is for a scientist responsible for delivering key non-clinical safety data both in traditional clinical pathology sciences as well as immune-safety for projects across the R&D portfolio. You will be an integral part of a high performing team that measures biomarkers for target-organ toxicity and adverse immune effects on nonclinical studies. You will contribute to the interpretation of the clinical relevance of your data as it supports safe progression of clinical candidates in patients. In this role you may perform the following job-related activities; together with other appropriate tasks, as requested by management:

Key Responsibilities and Accountabilities

• Focus of the job will cover both clinical pathology and immune-related biomarkers.
• Provide subject matter and technical expertise on relevant study endpoints.
• Perform testing/data analysis and interpretation related to clinical pathology laboratory analyses: hematology, clinical chemistry, coagulation, urinalysis, immunoassay-based biomarkers, blood smear, bone marrow smear and other relevant diagnostic capabilities to monitor animal health.
• Perform testing/data analysis and interpretation related to immune profiling: high dimensional flow cytometry, targeted transcriptomics, multiplex immunoassays and bioassays.
• Work cooperatively in a team that coordinates multiple simultaneous study activities.
• Responsible for generation of data tables/figures and written draft summaries of findings to support the reporting of study results. Ensure timely communication to the Study Director/Investigator of study related events and/or deviations.
• Support automation of laboratory workflows.
• Ensure scientific data integrity for accuracy and quality.
• Conduct work in accordance with study protocols, Standard Operating Procedures (SOPs), and GSK policies.

Why you?

Basic Qualifications:

We are looking for professionals with these required skills to achieve our goals:

• BS/MS in Clinical Laboratory Sciences/Medical Technology AND 5+ years of nonclinical/clinical laboratory and/or pharmaceutical industry experience

OR

• PhD in Immunology or Related Degree (e.g., Biomedical Research, Biology, or Cellular and Molecular biology)

Preferred Qualifications:

If you have the following characteristics, it would be a plus:

• Education with a focus on Immunology and/or Toxicology
• Hands on experience in multiple clinical pathology laboratory areas including hematology, clinical chemistry, and other relevant capabilities.
• Hands on experience in profiling immune biomarkers with state-of-the-art technologies (e.g., high dimensional flow cytometry, targeted transcriptomics, multiplex immunoassays and bioassays).
• Demonstrable experience in scientific critical thinking and independent planning, design and execution of experiments to test hypotheses.
• Proficiency in automated workflows.
• Experienced with compilation, analysis, visualization and interpretation of complex datasets.
• ASCP certification

• Experience with troubleshooting and resolving technical issues related to experimental processes or complex laboratory instrumentation.
• Demonstrable timely delivery of scientific data that meets acceptable data integrity standards.
• Experience in working closely with multidisciplinary teams and collaborating across organizational boundaries.

#LI-GSK

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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