• Job Description

  Req#: REQ-24715

  Job Description

  General Summary:

  The Process Chemistry Scientist will design and perform synthetic organic experiments efficiently, independently and fit-for-purpose chemistry for the stage of development (pre-clinical through P3) with a high degree of independence. This role will outline study designs, execute on complex experiments, and complete work in a self-sufficient manner.

  Key Duties and Responsibilities:

  • Performs reactions monitoring using a variety of analytical methods and work with analysts to develop sufficient methods.
  • Generates effective hypotheses to pursue synthesis or manufacturing goals and set new experimental direction.
  • Understands and develops synthetic plans for synthesis development of molecules.
  • Provides technical recommendations within the company regarding process chemistry by assisting other chemists in Process Chemistry and Development and/or articulating issues to upper management.
  • Makes conceptual contributions to development activities and scientific strategies; introduces some new methodologies and solutions to overcome synthetic and manufacturing obstacles.
  • Employs new principles and concepts from other fields to promote new progress in synthesis.
  • Develops familiarity with SOPs and GMPs and ensure compliance with all applicable regulations and SOPs.
  • Contributes to reports and regular updates at appropriate project intervals while maintaining detailed laboratory records.

  Knowledge and Skills:

  • Expanded conceptual understanding of their discipline, informed on relevant literature and aspects of drug development including regulations and compliance
  • Ability to provide data suitable for regulatory submissions
  • Recognized as a technical source within the department
  • Ability to provide informal guidance to new team members and mentor junior team members
  • Lab experience for the preparation of synthetic organic compounds
  • Experience in purification and data analysis of organic compounds
  • Excellent verbal and written communication skills to explain complex technical/scientific information to others in straightforward situations

  Education and Experience:

  • PhD with 0-3 years of experience or Master degree with 3+ years of experience Bachelor degree with 6+ years of experience or the equivalent combination of education and experience.

  Flex Designation:

  On-Site Designated

  Flex Eligibility Status:

  In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

  Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

  Company Information

  Vertex is a global biotechnology company that invests in scientific innovation.

  Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

  Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

• About the company

  Vertex Pharmaceuticals, Inc. is an American biopharmaceutical company based in Boston, Massachusetts.

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