• Job Description

  Req#: 1083308
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  We seek a highly self-motivated and organized individual to work on interdisciplinary collaborative projects in the Department of Medicine at Brigham and Women’s Hospital and Harvard Medical School. This work is supported by research grants funded by the National Institutes of Health. The project focuses on developing novel biomaterials in research and translational settings to better treat inflammatory conditions in the digestive system, particularly inflammatory bowel disease. The Postdoctoral Fellow will work on biomaterials-based drug delivery systems to promote healing in the gut. The ideal candidate will have a background in biomedical engineering and immunology research and expertise in animal experiments. Preferred experience includes biological analysis (qPCR, ELISA, etc.), analytical quantifications (HPLC, LCMS, etc.), or spectroscopic methods (¹H-NMR, UV-Vis, etc.).
  The Partners Research Building (PRB) at 65 Landsdowne Street is located at the University Park in Cambridge. The PRB hosts laboratories and researchers from Brigham and Women’s Hospital, Massachusetts General Hospital, and Partners HealthCare Personalized Medicine that operates the Laboratory for Molecular Medicine and the Translational Genomics Core. The PRB is adjacent to the Massachusetts Institute of Technology campus and close to the Longwood Medical Area. We conduct research that advances disease treatment and foster scientists who lead breakthrough research. The successful candidate will work with Dr. Sufeng Zhang and collaborate with a multidisciplinary team involving researchers at the Traverso Lab at Brigham and Women’s Hospital and Massachusetts Institute of Technology. We are a diverse group working with interdisciplinary collaborators and provide a supportive, team-based training environment engaging in ongoing collaborations across the Boston area and beyond.
  Responsibilities:
  The postdoctoral fellow will lead the project on drug delivery systems to treat chronic inflammation and promote healing in the gut. Primary responsibilities include independently performing research, such as nanoparticle synthesis and characterization, hydrogel formulation and characterization, drug release studies, and preclinical evaluation of the delivery systems in relevant animal models (efficacy studies, pharmacokinetics, toxicity, etc.). General responsibilities include documenting experimental procedures and interpreting results, analyzing and summarizing results, preparing scientific presentations and publications, interacting with IACUC/IRB to keep them up to date, and working with collaborators in a multidisciplinary team.
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  Qualifications:
  A Ph.D. or equivalent doctoral degree in Biomedical/Biological Engineering, Chemical Engineering, Chemistry, Biology, Pharmaceutical Science, or related field.
  One or more relevant experiences detailed below are preferred:
  · Drug delivery formulations (e.g., micro/nanoparticles, polymer coatings/matrices, and hydrogels).
  · Cell culture and animal work techniques, including flow cytometry, qPCR, tissue harvest and processing, and other techniques as needed.
  · Polymer synthesis and characterization (e.g., bioconjugation, free-radical polymerization, GPC, and ¹H-NMR).
  · In Vivo Imaging System (IVIS), fluorescence microscopy, and bright field microscopy.
  Interested candidates should email Dr. Sufeng Zhang (szhang@bwh.harvard.edu). Please attach an up-to-date CV and a list of three references. Applications will be reviewed promptly and accepted until the position is filled.
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  BWH is an Affirmative Action Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
  
  BWH Boston Main Campus (BWHMAIN)
  75 Francis St
  Boston, 02115
  
  

• About the company

  Brigham and Women's Hospital is the second largest teaching hospital of Harvard Medical School and the largest hospital in the Longwood Medical Area in Boston, Massachusetts.

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