• Job Description

  Req#: 3303439
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  GENERAL SUMMARY/ OVERVIEW STATEMENT:

  The Claussnitzer Laboratory in the Center for Genomic Medicine at Massachusetts General Hospital (MGH) is seeking a motivated, enthusiastic candidate to join our research group. The Claussnitzer lab at MGH will build a large-scale biobank of adipose-derived mesenchymal stem cells and other specimens with the aim to perform population-scale natural genetic variation screens. This effort will seek to systematically link genetic variation to molecular and cellular phenotypes in the context of metabolic disease.

  We are looking for a talented research technician who will contribute to build cell-based biobank and additional research efforts aimed at mapping genetic variations in metabolic cell types and understanding genetic regulation and cellular programs in health and metabolic diseases. This candidate will apply technologies combining the isolation of mesenchymal stem cells from different adipose depot, the isolation of hepatocytes and preparation of histology sections, execution of several molecular biology techniques to systematically link genetic risk variants to their effector genes and measure the impact on cellular metabolic functions using targeted assays and high-throughput and high-content profiling methodologies. Experience with basic and advanced techniques in molecular biology, cell culture and/or biochemistry is highly advantageous. Basic computer skills and previous laboratory experience are preferred.

  The Claussnitzer lab is a fun, fast-paced, impact-driven, collaborative environment, located at the Center for Genomic Medicine and Endocrine Division at MGH and Broad Institute and part of the greater Boston life-science community including MIT and Harvard. The workplace culture is diverse, dynamic, progressive, and supports a healthy work-life balance. To enable this mission, we strive to support diversity, intellectual curiosity, flexibility, and integrity .

  PRINCIPAL DUTIES AND RESPONSIBILITIES:

  • Prepares basic solutions and performs base-level procedures as assigned (i.e. – pipetting, cell and tissue culture, etc.)
  • Maintains laboratory notebook
  • Understands and applies basic scientific techniques
  • Conducts analysis of results and may begin interpretation of results
  • Sets up and prepares routine experiments as directed
  • Prepares lab reagents and chemicals, learn and handle instruments and equipment
  • May perform independent literature searches
  • Assists with organizing materials for publication or presentation
  • Maintains and orders supplies
  • Comply with all safety, biohazard, and other institutional rules.
  • Attend and participate in lab and project meetings, including preparing reports, slide decks and presenting progress.

  SKILLS/ABILITIES/COMPETENCIES REQUIRED:

  • Ability to work independently and as a team member
  • Good communication skills
  • Computer literacy
  • Working knowledge of clinical research protocols
  • Ability to perform multiple tasks independently

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  EDUCATION:

  Bachelor’s degree required.

  EXPERIENCE:

  New graduates with some lab experience (via course work, internships, etc.) or those without any prior research experience will be considered for the Research Technician I position outlined above.

  SUPERVISORY RESPONSIBILITY (if applicable):

  N/A

• About the company

  Mass General Brigham is a Boston-based non-profit hospital and physicians network that includes Brigham and Women's Hospital and Massachusetts General Hospital, two of the nation's most prestigious teaching institutions.

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