GSK is a global biopharma company with the ambition and purpose to unit science, technology, and talent to get ahead of disease together.

The US Structural Biology Center of Excellence (CoE), a new joint Vaccines and Pharma Center, will be established in Cambridge, MA in 2024. The mission of the CoE is to apply the full range of structural biology, biochemistry, and computational tools to design antigens, RNAs, delivery systems, and formulations for Vaccines as well as to design antibodies, biologics, and small molecules for Specialty Medicines and Oncology products.

We’re looking for a passionate and highly motivated scientific leader with demonstrated success in structural biology to join the CoE. The successful candidate will be an accomplished vaccine or medicine hunter and have utilized state-of-the-art expertise in cryo-EM and X-ray crystallography, driving discovery programs with structural information. The position will require active collaboration with diverse teams to work together and address key discovery challenges with the best scientific insights possible.

Key Responsibilities:

• Build internal structural biology capabilities and infrastructure appropriate to support GSK Vaccines and Pharma programs.
• Develop and implement external innovation strategies to enhance structural biology approaches through CROs and academic partnerships to advance the internal portfolio and complement internal capabilities.
• Provide leadership and expertise in protein biochemistry, structural biology and computational design as essential components of structure-based design efforts and platform evolution.
• Develop design strategies, screening funnels and other mechanistic studies to support lead identification, validation, and progression.
• Be fully integrated in cross-functional project and core teams, making substantial intellectual contributions to all levels of program strategy.
• Lead research activities and meetings.
• Stay scientifically cutting edge and identify emerging science to advance the portfolio and educate other colleagues.
• Be a scientific leader and mentor.

Why You?

Basic Qualifications:

• PhD. in a structural biology related field
• Five years or more experience in industry, post doctoral, or government lab setting.

Preferred Qualifications:

• Good knowledge and understanding of GSK Vaccines and Pharma strategy and objectives, regulatory requirements, as well as competition intelligence and intellectual property aspects. Ability to integrate this knowledge in decisions and recommendations.
• Practical expertise in cryo-EM/cryo-ET and other biochemical and biophysical methods.
• Strong track record of publication in peer reviewed journals, or patent filing.
• Experience of scientific leadership to influence programs of research.
• Excellent communication skills, need to appropriately manage the interfaces with Project Teams
• Fluency in English
• Able to efficiently manage uncertainty, changes in priority and timeline restrictions.

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why Us?

GSK is a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organization where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to positively impact the health of 2.5 billion people by the end of 2030.

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a workplace where everyone can feel a sense of belonging and thrive as set out in our Equal and Inclusive Treatment of Employees policy. We’re committed to being more proactive at all levels so that our workforce reflects the communities we work and hire in, and our GSK leadership reflects our GSK workforce.

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GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

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