• Job Description

  Req#: JOB ID-08978

  Are you an experienced Bioanalytical scientist with 2 years plus experience within a bioanalytical setting in the pharmaceutical industry or a contract research organisation? If so, then this could be the opportunity for you!

  Role: Scientist, Bioanalysis, Permanent

  Direct Report: to the Associate Principal Scientist, Bioanalysis

  Hours: Full time, 37.5 hours per week

  Salary: from £28,000 pa, dependant on skills and experience, excellent benefits package plus annual bonuses.

  Location: Alderley Park , Macclesfield, SK10 4TG.

  Our Company

  Cyprotex is part of the Evotec Group, a global leader in research. With state-of-the-art facilities and technical expertise, we provide innovative and bespoke assurance tailored to each of our client’s needs. Cyprotex specialises in in-vitro and in-silico ADME-Tox services. This includes in vitro ADME screening to support discovery projects, regulatory in vitro ADME and DDI studies during preclinical and clinical development, specialist mechanistic in vitro human and animal toxicity models (e.g., 3D models and MEA electrophysiology) and PBPK/QSAR modelling expertise. As well as supporting clients directly, we have a strong focus on R&D.

  Our Alderley Park site is set in the heart of Cheshire surrounded by a stunning 400-acre estate, open green spaces, and sweeping viewpoints, all within easy reach of Merseyside and Greater Manchester, Staffordshire, Derbyshire, and Shropshire. Easy access to public transport.

  As a result of year-on-year success within the company and continued business growth, exciting opportunities have arisen to join our team of highly skilled scientists in our Analytical Sciences team.

  As a Scientist, Bioanalysis you will be responsible for:

  Role and Responsibilities as our Scientist within the Bioanalysis Team

  We have a new opportunity for a Bioanalysis Scientist to join a dynamic and fast-moving team and be responsible for the bioanalytical aspect of in-vivo PK and PD studies. As a member of the bioanalytical team, you will be responsible for all aspects of bioanalytical support for PK and PD studies. The role will involve carrying out experiments to characterise rodent PK, PD responses as well as reviewing data and summarising PK and PD results.

  Additional interactions will be with other discovery departments at various Evotec sites to coordinate sample collections, analysis, and reporting in accordance with established timelines. The team uses modern mass spectrometry instrumentation, so you will be familiar with hands on LC-MS/MS operation and maintenance/troubleshooting. You should be highly self-motivated, well organised, diligent in record keeping, have an excellent working knowledge of the drug discovery process and be able to perform consistently at the highest level.

  Skills & Competencies (essential)

  • Development of suitable methods and interpretation of a variety of analytical techniques (such as accurate and nominal mass spectrometry) to characterise small and large molecules.
  • Experience of different sample preparation techniques including protein precipitation, SPE etc.
  • Consistent team player with strong communication and motivational skills.
  • Excellent organisational skill and close attention to detail.
  • Working knowledge and understanding of bioanalytical assay for small and large molecules from within a discovery, development or CRO setting.
  • Strong analytical skills, and a demonstrated ability to both independently and in team setting.
  • Sound knowledge of Pharmacokinetics as applied to invivo studies within drug discovery/development.
  • A sound knowledge of routine maintenance and troubleshooting on Sciex LC-MS/MS instruments.
  • Ability to learn and lead the implementation of new techniques and processes at a fast pace.
  • Communicate effectively between departments and contribute to the growth strategy of Analytical Sciences within Cyprotex.
  • Good time management skills and ability to work to tight deadlines.

  Education, Qualifications and Experience

  • BSc/MSc with 2 years of relevant hands-on LC-MS/MS experience in relevant scientific discipline covering biochemistry or related discipline.

  Desirable but not essential

  • Experience with Analyst™and/or MassLynx™ or other Mass Spectrometry data-acquisition software packages.
  • Experience with Phoenix Winnonlin™

  What we can offer you in return

  We offer a competitive salary and benefits package.

  • Pension on completion (but not subject to) of your 3-month probationary period. Contributions 6% for employees (salary sacrifice) and 6% for the employer. The employee can opt to increase their contribution and the employer will match the increase up to a maximum of 7.5%.
  • 25 days holiday plus bank holidays and additional length of service days awarded on the anniversary, up to a maximum of 30 days.
  • Private health insurance with BUPA for the employee and their partner/family under the company scheme.
  • Private dental cover, on completion (but not subject to) of your 3-month probationary period.
  • Wellbeing support 24/7 and counselling services
  • Permanent health insurance provides 75% of the base salary after the qualifying period.
  • Eligibility to participate in the Company Bonus Scheme. This is a discretionary benefit.
  • Career progression within the company, we have excellent training and support and continuing professional development opportunities.
  • Cycle-to-work scheme
  • Refer a friend scheme, team and annual events, recognition awards and many more!

  Onsite Facilities

  • The company pays for secure onsite parking.
  • Restaurant, café, and a gastro pub
  • Gym and workout studio, running, walking, and cycling routes.
  • Good public transport links with the shuttle bus service.

  Interested?

  Apply NOW – please upload your up-to-date CV and cover letter to Workday.

  If you have any questions, please contact Sarah Lomas, Senior Specialist Global Talent Acquisition via LinkedIn. to view our current vacancies and more information about the company visit our careers page – Evotec.

  Evotec is proud to be an equal opportunities employer, welcoming individuals regardless of age, gender, sexual orientation, marital status, race, nationality, religious denomination, or disability. We match our role based on your suitability and experience.

  Candidates must have the right to work in the UK. We will consider European applications with the right skills and experience. All roles will be subject to a security screening check.

  Due to the high volume of applications, we may close this vacancy at any time once we find our perfect match.

  **Direct applications only – No agencies please.

  #cyprotex #scientistjobs #bioanalyticalscientist #pharmaceuticaljobs #drugdiscovery #dmpkscientist #cheshirejobs #macclesfieldjobs #Researchneverstops

  FR : Dans le cadre de sa politique Diversité, Evotec étudie, à compétences égales, toutes les candidatures dont celles des personnes en situation de handicap.

  ENG : In the frame of our Diversity policy, Evotec considers, with equal competences, all applications including people with disabilities.

• About the company

  Contact us to learn more about our full range of ADME, PK and toxicity services for the pharmaceutical, cosmetics, personal care and chemical industries - high quality robust data

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