We are looking for an enthusiastic Bioinformatics Scientist to work in close collaboration with scientists from diverse fields and who can lead independent scientific projects. You will develop and maintain innovative bioinformatics methods and computational pipelines running on high-performance computing platforms that help the Regeneron Genetics Medicines group create next generation therapies using gene editing and gene insertion. Your role will involve working on innovative technologies like Adeno-associated viruses, CRISPR-Cas9, deep mutational scanning, and using machine learning methods to treat of cure disease. Working in the Molecular Profiling and Data Science department will also give you the opportunity to participate in collaborations in many facets of research and development, ranging from machine learning and inference of statistical models for genotype-phenotype assay data through to the assessment of therapeutic antibodies and other biologics that drive Regeneron’s therapeutics.

As a Scientist-Bioinformatics, a typical day might include the following:

• Develop and maintain bioinformatics pipelines and carry out bioinformatics analysis using languages such as Shell, Python, and R, and use HPC platforms in a Linux/cloud-based environments.

• Develop machine-learning and statistical frameworks to get insights from large sequencing data sets and work on generative models to optimize and generate novel biological sequences with desired properties.

• Building tools to characterize gene insertion and analyze NGS data using short and long-read sequencing.

• Work with other bioinformaticians to enhance existing pipelines, share methodologies, and develop standard processes.

• Conduct independent computational biology research aligned with the department’s overall goals.

• Collaborating extensively with wet-lab biologists to design the best experiments and NGS readouts.

This job might be for you if:

• Want to contribute to the advancement and design of next generation genetic therapies and improve health outcomes.

• Like working at the interface between computation and experiments.

• Have a strong computational background and enjoy creating new methods.

• Like diving deep into data, including analyzing raw NGS reads.

• Can effectively communicate complex concepts to collaborators from a wide range of backgrounds.

• Want opportunities to showcase and publish your work.

To be considered for this role, you must have a PhD degree (or master’s degree with 4 years of relevant experience) in Computational Biology, Bioinformatics, Quantitative Biology, Computer Science, Applied Mathematics, Physics, or related quantitative fields. You must have experience conducting bioinformatics analysis at either the gene or sequence level, have experience with machine learning methods, and have a strong background (3+ years) in Python and/or R. Strong familiarity in working in a Linux environment, and shell scripting is desirable. Strong familiarity with HPC environments is also high valued. Familiarity with code version control systems such as git and testing code (e.g., unit- and functional-tests) a strong plus. Experience with front-end web application development would be a plus.

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Does this sound like you? Apply now to take your first steps toward living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits including health and wellness programs, fitness centers and equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. We will ensure that individuals with disabilities are provided reasonable accommodations to participate in the job application process. Please contact us to discuss any accommodations you think you may need.

The salary ranges provided are shown in accordance with U.S. law and apply to U.S. based positions, where the hired candidate will be located in the U.S. If you are outside the U.S, please speak with your recruiter about salaries and benefits in your location.

$88,500.00 - $144,500.00