• Job Description

  Req#: R-01188672

  Job Description

  Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing productivity in their laboratories, we are here to support them.

  Location/Division Specific Information

  West Hills, CA / Transplant Diagnostics

  How will you make an impact?

  With your broad spectrum of working knowledge and experience in mammalian cell culture, protein expression and characterization, flow cytometry, cell line generation, and cell banking with scientific rigor in a regulatory environment, you will be part of the Cell Biology R&D team that supports development, production, and quality of our in vitro diagnostics (IVD) products for antibody detection.

  What will you do?

  • Maintain mammalian cell culture including thawing, passaging, expansion, cell banking, and inventory management.
  • Generate recombinant cell lines including transfection, selection, enrichment, single cell cloning, clonal expansion, and banking.
  • Establish Epstein-Barr virus transformed cell lines from PBMCs.
  • Characterize cell lines by cell viability analyzer, antigen expression by flow cytometry, cell line identity by molecular typing, and cell line sterility by mycoplasma testing.
  • Purify antigen or antibody. Perform biochemical and biophysical characterizations including concentration determination, SDS-PAGE, Western Blot, dynamic light scattering (DLS), ELISA, Octet, and Luminex.
  • Perform studies or investigations under the mentorship of Cell Biology manager.
  • Carry out lab duties including preparing buffers, reagents and media, maintaining lab supplies, and supporting other functions in the group.
  • Compile and analyze data to complete an update or report.
  • Give oral presentations at internal meetings.
  • Perform all activities in compliance with GDP, GMP, regulatory and safety policies.

  How will you get here?

  Education

  PhD or MSc degree in Cell Biology, Molecular Biology, Biochemistry, Immunology, Genetics or a related disciple in Biological Sciences

  Experience

  • 3+ years of post-graduate or industry experience, preferably in the development of therapeutics or diagnostics
  • Experience in assay development characterizing antigen-producing cell lines and antigen-antibody interactions is helpful
  • Molecular cloning experience in expression vector design and construction for recombinant protein expression in mammalian cells
  • Demonstrated knowledge in cell biology, immunology, HLA, lymphocyte development and transplantation
  • Clear understanding of cell culture, cell line development and cell banking principles and practices
  • Proficiency in flow cytometry, software, database

  Knowledge, Skills, Abilities

  • Excellent communication, documentation (organization and record-keeping), and presentation skills
  • Ability to perform multi-tasks and manage priorities to meet company goals
  • Strong problem-solving skills, identifying root causes, and proposing alternative approaches and feasible solutions
  • Ability to work both independently and collaboratively in a group setting to meet project timeline
  • Ability to work in a cross functional environment
  • Flexibility and adaptability in a highly dynamic and demanding environment

  This position has been approved for relocation assistance.

  Our Mission is to enable our customers to make the world healthier, cleaner and safer. Watch as our colleagues explain 5 reasons to work with us. As one team of 100,000+ colleagues, we share a common set of values - Integrity, Intensity, Innovation and Involvement - working together to accelerate research, solve complex scientific challenges, drive technological innovation and support patients in need. #StartYourStory at Thermo Fisher Scientific, where diverse experiences, backgrounds and perspectives are valued.

  Apply today! http://jobs.thermofisher.com

  Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

  Accessibility/Disability Access

  Job Seekers with a Disability: Thermo Fisher Scientific offers accessibility service for job seekers requiring accommodations in the job application process. For example, this may include individuals requiring assistance because of hearing, vision, mobility, or cognitive impairments. If you are a job seeker with a disability, or assisting a person with a disability, and require accessibility assistance or an accommodation to apply for one of our jobs, please submit a request by telephone at 1-855-471-2255*. Please include your contact information and specific details about your required accommodation to support you during the job application process.

  This telephone line is reserved solely for job seekers with disabilities requiring accessibility assistance or an accommodation in the job application process. Messages left for other purposes, such as not being able to get into the career website, following up on an application, or other non-disability related technical issues will not receive a response.

  Compensation and Benefits

  The salary range estimated for this position based in California is $91,700.00–$110,000.00.

  This position may also be eligible to receive a variable annual bonus based on company, team, and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on, which includes:

  • A choice of national medical and dental plans, and a national vision plan, including health incentive programs

  • Employee assistance and family support programs, including commuter benefits and tuition reimbursement

  • At least 120 hours paid time off (PTO), 10 paid holidays annually, paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave), accident and life insurance, and short- and long-term disability in accordance with company policy

  • Retirement and savings programs, such as our competitive 401(k) U.S. retirement savings plan

  • Employees’ Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

  For more information on our benefits, please visit: https://jobs.thermofisher.com/global/en/total-rewards

• About the company

  Thermo Fisher Scientific is an American provisioner of scientific instrumentation, reagents and consumables, and software and services to healthcare, life science, and other laboratories in academia, government, and industry.

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