• Job Description

  Req#: R-173528

  Career Category

  Research

  Job Description

  HOW MIGHT YOU DEFY IMAGINATION?

  If you feel like you’re part of something bigger, it’s because you are. At Amgen, our shared mission—to serve patients—drives all that we do. It is key to our becoming one of the world’s leading biotechnology companies. We are global collaborators who achieve together—researching, manufacturing, and delivering ever-better products that reach over 10 million patients worldwide. It’s time for a career you can be proud of.

  Senior Data Scientist - Computational Chemistry

  Live

  What you will do

  Let’s do this. Let’s change the world. We are actively seeking a highly qualified and motivated Sr. Data Scientist with a strong background in cheminformatics and AI/ML. The scientist will join the computational chemistry team within Amgen’s Center for Research Acceleration and Digital Innovation (CRADI). CRADI functions within our drug discovery engine to accelerate our pipeline from target inception through drug development. The computational chemistry team develops and applies tools to generate novel molecules and predict chemical properties to guide the discovery of small molecule therapeutics. In this vital role, you will collaborate with a multi-disciplinary team of scientists to train, deploy, and maintain ML models for small molecule data. Furthermore, you will play an active role in developing software packages used by both computational and medicinal chemists for drug discovery projects. An ability to communicate clearly and collaborate effectively with colleagues from different fields will be essential. This position is a senior scientific role with significant leadership responsibilities and opportunities.

  Responsibilities:

  • Participate on multiple interdisciplinary discovery project teams and play a key role in data collection, model training and deployment for chemical property prediction
  • Apply structure-based, ligand-based and machine learning/generative design to guide experimental efforts
  • Collaborate with engineers and data scientists to develop innovative cheminformatics tools that facilitate data access, model utilization, and output interpretation
  • Clearly document methods and analyses to allow reproducible research
  • Monitor, review, and critically interpret published computational research spanning small molecule computer-aided drug design
  • Proactively scope and deploy novel ML/AI methods for chemical property prediction and molecule generation
  • Take an active leadership role in guiding new Machine Learning and Artificial Intelligence technology developments
  • Take an active leadership role in guiding infrastructure improvements, software portfolio recommendations and prospecting of relevant cutting-edge computational technologies/companies
  • Mentor junior data scientists

  The preferred location for this position is at our Thousand Oaks (CA) site; but consideration will be given to remote candidates as well

  Win

  What we expect of you

  We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

  Basic Qualifications:

  Doctorate degree and 2 years of Cheminformatics and ML experience

  Or

  Master’s degree and 6 years of Cheminformatics and ML experience

  Or

  Bachelor’s degree and 8 years of Cheminformatics and ML experience

  Or

  Associate’s degree and 10 years of Cheminformatics and ML experience

  Or

  High school diploma / GED and 12 years of Cheminformatics and ML experience

  Preferred Qualifications:

  • PhD. in computer science, computational chemistry, or related field
  • Fluency in scientific programming and tool development with Python
  • Proven record of innovative thinking to propose and champion the development of novel algorithms and AI/ML models that generate interpretable and actionable results for practical applications
  • Experience with software development best practices, including code versioning, documentation, and testing, amongst others
  • Experience with deep learning frameworks (e.g., PyTorch)
  • Experience with cloud computing
  • Creative, open-minded and passionate about scientific research
  • Demonstrated ability to thrive in a team environment
  • Strong external publication record

  Thrive

  What you can expect of us

  As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.

  The annual base salary range for this opportunity in the U.S. is $152,838 - $181,535.

  In addition to the base salary, Amgen offers a Total Rewards Plan comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities including:

  • Comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans and bi-annual company-wide shutdowns
  • Flexible work models, including remote work arrangements, where possible

  Apply now

  for a career that defies imagination

  Objects in your future are closer than they appear. Join us.

  careers.amgen.com

  .

  Salary Range

  152,838.00 USD - 181,535.00 USD

• About the company

  Amgen is one of the world’s leading biotechnology companies. Amgen is a values-based company, deeply rooted in science and innovation to transform new ideas and discoveries into medicines for patients with serious illnesses.

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