• Job Description

  Req#: R2760047

  Senior Scientist, Checkpoint Immunology

  About the Job

  We are an innovative global healthcare company that helps the world stay ahead of infectious diseases by delivering more than 500 million vaccine doses a year. Across different countries, our talented teams are exploring new technologies to protect people and promote healthy communities. We chase the miracles of science every single day, pursuing progress to make a real impact on millions of patients around the world.

  The Immunology and Inflammation Research Therapeutic Area in Sanofi is seeking highly motivated scientist to lead projects evaluating novel therapies in the fields of Immune Checkpoint Biology to treat autoimmune and inflammatory diseases. The scientist will lead new drug discovery programs from the early stage to the identification and validation of a clinical candidate. The successful candidate will have deep expertise in Immunology, autoimmune disease biology and demonstrated track record in leading scientific and/or drug discovery programs.

  The successful candidate will have deep expertise in Immunology, autoimmune disease biology, and a demonstrated track record in leading scientific and/or drug discovery programs. The scientist is expected to support early research programs as well as given an opportunity to lead a new project(s) by contributing one's scientific knowledge and technical skills to the growth of the Sanofi's checkpoint immunology portfolio. She/He will design and execute experiments to validate checkpoint targets for various I & I prioritized indications. The candidate will work in a matrixed environment and collaborate extensively with multidisciplinary platform groups to advance the portfolio projects.

  Key Responsibilities:

  • Responsible for applying scientific expertise and judgement to initiate, design and conduct preclinical studies to validate the target and to support the project transitions in timely fashion.

  • Uses novel experimental approaches within Checkpoint immunology and project team; routinely investigates/creates innovative processes, hypotheses and methodologies. Developing own strategy for drug discovery.

  • Collaborate with Immunology and Inflammation Bioinformatics Team to identify and validate therapeutic targets.

  • Provide scientific expertise, establish and manage external scientific collaborations, monitor the external market, and provide critical project assessments.

  • Makes decisions that frequently require developing new options to solve moderately complex problems. Works in ambiguous situations within therapeutic area/platform.

  • Uses a high level of scientific judgement to adapt and/or create standard methods and techniques by applying breadth of knowledge and prior work experience.

  • Works independently on assignments using knowledge and work experience. Gathers input from colleagues and management to address issues at therapeutic area level.

  • Provide and promote support for operational excellence according to Sanofi values and ethics.

  • Prepare publications, research and clinical/regulatory documentation in accordance with Sanofi quality standards.

  About you

  Basic Qualifications:

  • PhD plus a minimum of 3-4 years of relevant experience preferably in pharma/biotech set up.

  • Leading edge knowledge of Checkpoint Immunology including co-inhibitory/-stimulatory pathway biology, T/B or innate immunity and relevant experience in the immunology/inflammation-related disease areas.

  • Candidate should possess a strong understanding of biological concepts, mechanistic elucidation, and phenotypic workflows coupled with a strategic vision of novel target drug discovery

  • The job requires mostly benchwork and project leadership

  • Strong knowledge of immune receptor signal transduction and its implication in immune modulation (expertise in western blotting, immunoprecipitation) is a plus.

  • Expertise in various in vitro immunological assays and in vivo inflammatory models is required.

  • Outstanding track record of scientific publications, presentations, patents, projects as a leading contributor or senior author.

  • Established track record of leading drug discovery programs would be preferred.

  • Flexibility to adopt to a rapidly to changing priorities and deadlines and ability to lead others through change in a dynamic, fast paced industry and work environment.

  • Excellent interpersonal and communication skills: impactful oral and written communication.

  Why Choose Us?

  • Bring the miracles of science to life alongside a supportive, future-focused team.

  • Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.

  • Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.

  • Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

  Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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  Pursue progress, discover extraordinary

  Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

  At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

  Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

• About the company

  Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health.

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