• Job Description

  Req#: 47918

  Overview

  This position is in the Center for Perinatal Research in Dr. Thomas Lynch’s lab. We are seeking a motivated postdoctoral scholar to join our lab group. Our team is focused on developing basic and translational models of lung disease. Specifically, we use ferrets to address open knowledge gaps in pulmonary physiology and lung epithelium function, maintenance, and regeneration. The postdoc will be expected to advance scientific studies and develop hypotheses for further investigation with her/his/their results. A successful postdoc is expected to prepare technical materials such as abstracts, annual reports, scientific papers and presentations; publish scientific articles in appropriate refereed journals; works toward a goal of becoming independent in her/his/their research effort; and apply for and eventually obtain external research funding. A Post Doc is an appointment with a maximum of 5 years in length.

  Dr. Lynch’s research Profile:

  Dr. Lynch is a new principal investigator in the Center for Perinatal Research. His research interests aim to bridge critical gaps in understanding lung disease to facilitate the discovery of new therapeutics.

  Previously, Dr. Lynch was a K99 NHLBI research scholar and postdoctoral research fellow in the department of surgery within the University of Iowa, where he trained under the co-mentorship of Drs. Kalpaj Parekh and John Engelhardt. His work focused on chronic rejection following lung transplantation with a focus on lung stem cells and their microenvironments.

  Throughout his tenure at the University of Iowa, he authored 27 publications. Notably, Dr. Lynch’s publications focus on using small and large animal models to investigate airway epithelial stem cells, revealing and addressing critical knowledge gaps in lung epithelial regeneration. He has also begun to interrogate mechanisms of stem cell depletion using longitudinal single-cell RNA sequencing analysis.

  Responsibilities

  • Isolate and culture primary mammalian lung cells.
  • Perform experiments utilizing advanced flow cytometry, microscopy, and molecular biology techniques.
  • With guidance from a mentor, design experiments and develop protocols required to conduct productive research in a lung biology. After the study has been designed, performs the research work in accordance with the protocol.
  • Helps to train and supervise technical support staff in performing specific techniques essential to carrying out the research program.
  • Records and analyzes data generated by the research study and helps to plan future research endeavors.
  • Prepares scientific and technical papers from the results of the research work. Publishes papers in appropriate refereed scientific journals. Presents findings at local and national research forums.
  • When appropriate, collaborates with other ongoing research efforts in the lab and surrounding labs.
  • This is considered a training position therefore the RI will allow a trainee 5 years to advance beyond the level of Post Doc.
  • Works toward research independence. Prepares to submit proposals to and obtain funding from external granting agencies.

  Qualifications

  • PhD in Biomedical Sciences, Molecular Biology, Physiology, or related field
  • Expertise in DNA damage and repair pathways and is strongly preferred
  • Ability to draft technical manuscripts, maintain laboratory records, and communicate effectively

  EOE M/F/Disability/Vet

• About the company

  Nationwide Children's Hospital is a nationally ranked pediatric acute care teaching hospital located in Columbus, Ohio.

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