Johns Hopkins University
Proteomics Specialist
This job is now closed
Job Description
- Req#: 111019
- The individual should have a sophisticated understanding of techniques and a solid foundation in the underlying science, gained from prior research experience.
- The successful candidate will develop and implement state-of-the-art mass spectrometry-based methods to identify, characterize and quantify proteins from complex protein mixtures such as cell lysates and human plasma samples submitted by Johns Hopkins Investigators.
- In addition, the candidate will operate and maintain a high-resolution tandem mass spectrometers such as Thermo Scientific Orbitrap Exploris, Lumos and Q-Exactive and the requisite nano-scale liquid chromatography and capillary electrophoresis systems.
- Operate and maintain highly technical mass spectrometers and two-dimensional chromatographic or electrophoresis equipment.
- Identify, advise or assist investigators with developing strategies for sample preparation for the use of gel electrophoresis, liquid chromatography, capillary electrophoresis and mass spectrometry to identify, quantify and characterize proteins and their modifications.
- Expand or develop new skills, as needed, based on information from literature, in collaboration with other laboratories or vendors, or by interacting with colleagues at meetings or professional presentations.
- Teach staff, students or fellows advanced techniques in protein analysis by mass spectrometry used in the center through informal discussions or formal workshops offered by the facility.
- The position also implies daily supervision of all aspects of the center functioning.
- Responsible for maintaining high-end mass spectrometers, developing and following SOPs, developing and maintaining collaborative connections with the investigators.
- The successful candidate will be involved in biomedical projects. Independent research in technological developments in proteomics will be strongly encouraged.
- Mass Spectrometers (Orbitraps Explorises, Lumos ETD, Q-Exactive Plus, Voyager DE-STR MALDI-TOF)
- Liquid chromatography (nanoflow, capillary flow, affinity, reverse phase, cationic exchange)
- Capillary Electrophoresis.
- Master’s Degree in Biology, Chemistry or related experience is required.
- Two years experience with protein/peptide separation and analysis by liquid chromatography - mass spectrometry.
- Expertise in quantitative proteomics using label free (PRM, DIA) or labeling techniques (iTRAQ, TMT, SILAC or NeuCode).
- Must have good communication skills, be able to work independently, under minimal supervision with strong decision making skills and good judgment.
We are presently seeking a very disciplined and highly self-motivated individual to assist in the group as a Proteomics Specialist to join the Mass Spectrometry and Proteomics Facility at Johns Hopkins School of Medicine, Baltimore, MD.
Specific Duties & Responsibilities
Instrumentation Handled
Minimum Qualifications
Preferred Qualifications
Special Knowledge, Skills, & Abilities
Classified Title: Proteomics Specialist
Role/Level/Range: ACRP/04/ME
Starting Salary Range: Min $64,000 - Max $112,200 Annually ($84,000 targeted; Commensurate with experience)
Employee group: Full Time
Schedule: 5 days/37.5 hours
Exempt Status: Exempt
Location: School of Medicine Campus
Department name: BiolChem Fac/Staff
Personnel area: School of MedicineTotal Rewards
The referenced salary range is based on Johns Hopkins University’s good faith belief at the time of posting. Actual compensation may vary based on factors such as geographic location, work experience, market conditions, education/training and skill level. Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines:
JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.
**Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.
The successful candidate(s) for this position will be subject to a pre-employment background check. Johns Hopkins is committed to hiring individuals with a justice-involved background, consistent with applicable policies and current practice. A prior criminal history does not automatically preclude candidates from employment at Johns Hopkins University. In accordance with applicable law, the university will review, on an individual basis, the date of a candidate’s conviction, the nature of the conviction and how the conviction relates to an essential job-related qualification or function.The Johns Hopkins University values diversity, equity and inclusion and advances these through our key strategic framework, the JHU Roadmap on Diversity and Inclusion.
Equal Opportunity Employer
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
EEO is the Law
Learn more:
https://www.eeoc.gov/sites/default/files/migrated_files/employers/poster_screen_reader_optimized.pdfAccommodation Information
If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the Talent Acquisition Office at jhurecruitment@jhu.edu. For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations or accessibility at Johns Hopkins University, please visit accessibility.jhu.edu.
Johns Hopkins has mandated COVID-19 and influenza vaccines, as applicable. The COVID-19 vaccine does not apply to positions located in the State of Florida. Exceptions to the COVID and flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry. For additional information, applicants for SOM positions should visit https://www.hopkinsmedicine.org/coronavirus/covid-19-vaccine/ and all other JHU applicants should visit https://covidinfo.jhu.edu/health-safety/covid-vaccination-information/.
The following additional provisions may apply, depending on campus. Your recruiter will advise accordingly.
The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.
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About the company
The Johns Hopkins University is a private research university in Baltimore, Maryland.