• Job Description

  Req#: R03253

  The job details are as follows:

  What We Do

  We build on the strength of our research and development expertise and a distinctive, entrepreneurial culture that encourages diversity, innovation, creativity, sustainability, and, simply, fun. Since inception, our mission has been to find a cure for pulmonary arterial hypertension and other life-threatening diseases. Toward this goal we have successfully gained FDA approval for five medicines, we are always conducting new clinical trials, and we are working to create an unlimited supply of manufactured organs for transplantation.
  

  We are the first publicly-traded biotech or pharmaceutical company to take the form of a public benefit corporation (PBC). Our public benefit purpose is to provide a brighter future for patients through (a) the development of novel pharmaceutical therapies; and (b) technologies that expand the availability of transplantable organs. At the same time, we seek to provide our shareholders with superior financial performance and our communities with earth-sensitive energy utilization.
  

  Our company was founded by an entrepreneur whose daughter was diagnosed with a life-threatening condition. She sought to find treatment options and a cure for her daughter and patients like her. We are founder-led, and relentless in our pursuit of “medicines for life”. We continue to research and develop treatments for cardiovascular and pulmonary diseases, and other orphan diseases.

  Millions worldwide are living with chronic kidney disease (CKD) or diabetes. Management and maintenance therapies are ongoing, expensive and often undermine the person's quality of life. Their only hope for cure is an organ transplant. At Iviva, a subsidiary of United Therapeutics Corporation, we are working to transform the status quo by developing advanced organ therapeutics that can offer patients with organ dysfunction a cure and a normal life.
  
  
  How you’ll contribute
  The Research Associate II is responsible for helping to derive and expand the necessary cell types to develop and build autologous tissue constructs as a solution to end-stage renal disease and other disorders. This position is part of a multidisciplinary team led by experienced stem cell and developmental biologists and engineers. This individual is experienced in human primary cell and stem cell derivation, expansion, and differentiation. Technical expertise in multiple cell biology techniques including quantitative polymerase chain reaction, fluorescence microscopy, flow cytometry and other immune-based assays are critical to this position.

  • Perform and optimize cellular processes to support the production of iPS-derived renal cells
  • Perform and optimize the processes to expand and differentiate iPS cells into various cell types
  • Assist in cell studies to address technical and scientific challenges to expansion and differentiation of iPSC-derived cells
  • Record and manage use of materials and reagents needed to carry out experiments
  • Write and update standard operating procedures and batch records for various differentiation processes
  • Write and update standard operating procedures for operation and maintenance of laboratory equipment
  • Conduct the technical transfer of assays into the production team or to internal manufacturing, as needed
  • Meet 1:1 with managers to review results and progress
  • Maintain smooth operations of the lab, including maintenance of lab supplies, monitoring of equipment, providing general lab support, and helping identify areas for improvement
  • Follow proper procedures regarding laboratory safety, use of personal protective equipment, and handling of biohazard materials, including human or animal cells and tissues
  • Record all laboratory data in the in-house data management system(s)
  • Perform other duties as assigned

  
  For this role you will need

  Minimum Requirements

  • Bachelor’s Degree in cellular biology, developmental biology, biomedical engineering or related field and 2+ (5 for Senior) years of experience in a cell biology, developmental biology or biomedical engineering environment in industry (with a Bachelor's Degree) OR Master’s Degree in cellular biology, developmental biology, biomedical engineering or related field (with 3 years of related work experience for Senior)
  • Technical expertise in iPSC maintenance and differentiation methods
  • Aseptic Technique and mammalian cell culture
  • Knowledge of cell biology
  • Ability to initiate and manage day-to-day tasks effectively, including multi-tasking, flexibility and adaptability
  • Ability to independently follow experimental methods and protocols
  • Comfortable working in a hands-on laboratory environment and have good attention to detail and good lab practices
  • Strong attention to detail
  • Knowledge of flow cytometry and other cell sorting and analysis techniques

  Preferred Qualifications

  • Technical experience in cell bioreactor culture
  • Experience using scientific rules and methods to solve problems.
  • Experience using mathematics to solve problems.
  • Technical expertise in cellular process development

  At United Therapeutics, you’ll realize quickly that it is not an ordinary place to work! When you join our company, you will learn, grow, contribute, have fun, and be challenged... all while making a difference in the lives of our patients.

  While United Therapeutics does not require vaccination for Covid-19 at this time, we strongly encourage all employees and visitors to remain up to date on vaccinations and boosters to protect one another from illness. Employees working in customer-facing roles must adhere and comply with customers’ credentialing guidelines, which may require vaccination against Covid -19, the influenza virus, and other illnesses that could be harmful to healthcare staff and patients.

  United Therapeutics Corporation is an Equal Opportunity/Affirmative Action Employer - EOE Minorities / Females / Protected Veterans / Individuals with Disabilities

• About the company

  United Therapeutics is a biotechnology company listed on the NASDAQ.

Notice