• Job Description

  Req#: 299755

  About the Department

  Our Boston Research & Development hub, anchored in the greater Boston area, brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown and Cambridge reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our greater Boston R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.
  
  The team is comprised of collaborative, diverse and passionate people who have a true sense of pride in their work and are committed to helping others grow and develop their careers. You’ll also have a platform to engage with key stakeholders on a global scale throughout the entire pipeline process. And while changing the future of diabetes, obesity and MASH is no easy task, we also recognize the importance of an enjoyable workplace, which is why we’ve cultivated a culture of fun, ingenuity and innovation. And our competitive compensation package and support of a healthy work-life balance all add to a best-in-class employee experience. We are changing lives for a living. Are you ready to make a difference?

  The Position

  Our US Research & Development hub, located in the Greater Boston area, brings together the best talent to drive life science innovation. Located in Lexington, Watertown and Cambridge, our teams reflect the full scope of R&D, from early research through late-stage clinical development. We are building for the future by creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. By combining the speed and agility of biotech with the quality, resources, and stability of a large pharmaceutical company, our US R&D hub will benefit from the best of both worlds to develop new medicines that meet the needs of patients.

  Global Drug Discovery (GDD) is establishing a dedicated microphysiological systems (MPS) department in Watertown with the purpose of identifying and integrating the next generation of human disease models into our drug discovery efforts. The department will be anchored in the Integrated Physiology Research area and will have strong integration with the biology areas across GDD.

  The Associate Scientist will be part of a highly ambitious multidisciplinary team dedicated to setting up and implementing human cell-based disease relevant MPS platforms to support validation and progression of early drug candidates. Working closely with the cardiometabolic therapeutic areas across the Research & Early Development (R&ED) organization the individual will help develop, validate, and implement organ-specific disease models with the initial focus of developing multicellular cardiometabolic disease models. The associate Scientist will work hands-on in the lab performing MPS-related in vitro cell work (culture and differentiation of primary cells as well as cell lines). Furthermore, the job entails setting up and performing advanced analytical methods. Moreover, the Associate Scientist will help establish this new unit by technical laboratory expertise to establish the entire workflow from frozen cells to analysis results.

  Relationships

  The Associate Scientist will report to the head of the Microphysiological Systems (MPS) department at Novo Nordisk in Greater Boston (Watertown).

  Internal relationships include working closely with technical staff and scientists within the MPS department as well as with the head of MPS. Moreover, the individual will work closely with scientists within the cardiometabolic therapeutic areas across the global Research & Early Development (R&ED) organization.

  The Associate Scientist may interact with external research collaborators within academia- & industry.

  Essential Functions

  • Hands-on responsibility for planning, executing, analyzing and present data from advanced in vitro models (MPS).
  • Provides scientific or technical input and training related to primary cell culture, sample processing, biochemical analysis.
  • Analyzes data with high degree of sophistication, connecting disparate datasets to reach conclusions, and suggesting direction on experiments.
  • Responsible for drafting study protocols and electronic lab notebook reports with limited supervisor input.
  • Makes recommendations for new procedures and continuously focuses on optimizing current processes and procedures
  • Effectively communicates and presents ideas and data to cross-functional local and global project teams.
  • Studies scientific literature to support research projects and expands the capabilities of scientific research through the evaluation of methodology and implementation of new technologies.
  • Share better practice sharing and implementation within the research environment.
  • Develops enhanced cross-cultural understanding to effectively interact with relevant stakeholders in the global organization.
  • Manages site inventory. Orders laboratory supplies and equipment. Maintains the laboratories and performs other job-related duties as assigned
    

  Qualifications

  • Education Level: BS/BA. At least 6 years relevant technical experience required; Master’s degree + 2 years relevant experience can be considered
  • The individual works independently on projects of moderate complexity & with limited instruction for activities of high complexity. Can perform highly complex task and demonstrates high degree of method or technical knowledge

  • The individual works independently on projects of moderate complexity & with limited instruction for activities of high complexity. Can perform highly complex task and demonstrates high degree of method or technical knowledge

  • The Associate Scientist has extensive experience within multiple of the following areas:
    - Culture of mammalian cells and tissues
    - Molecular biology techniques
    - Standard analytical methods e.g., RNAseq, PCR, Flow cytometry, cell sorting, ELISA/multiplex
    - Workflow automation
    - High content imaging
    - Programming (Python or R)
    - scRNAseq
    - Cardiometabolic disease biology

  We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.

  At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we’re life changing.

  Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.

  If you are interested in applying to Novo Nordisk and need special assistance or an accommodation to apply, please call us at 1-855-411-5290. This contact is for accommodation requests only and cannot be used to inquire about the status of applications.

• About the company

  Novo Nordisk A/S is a Danish multinational pharmaceutical company headquartered in Bagsværd, Denmark, with production facilities in eight countries, and affiliates or offices in 5 countries.

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